Dr Giovanni Settanni
Theoretical and computatational biophysics
Since the discovery of the one-to-one
correspondence between protein sequences and their unique three
dimensional structure many aspects of the folding process of proteins
have been
elucidated, although a non-anecdotal and synthetic view of the
problem is still elusive. Theoretical and computational approaches
have helped to explain the basic physical principles underlying a
folding system and some important features of the free energy
landscape of proteins. With the steady increase in available computer
power,
computational methods are an increasingly important tool for studying
the folding, dynamics and interactions of biological molecules.
Here, we apply these methods to study several interesting biological
system and develop novel analysis instruments able to synthesize the
results of our simulations in a productive way.