UMC Mainz
Unit "Responses to DNA Lesions" (AK Khobta) 
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Andriy Khobta, Ph.D., Dr. habil.

Group Leader “Responses to DNA Lesions”

Institute of Toxicology,

University Medical Center Mainz,

Obere Zahlbacher Strasse 67

Phone (ITOX): +49 6131 17-9271

Email: khobta|at|uni-mainz.de

Andriy
 
 
  ACADEMIC DEGREES / QUALIFICATIONS

2013

Habilitation (Pharmacology and Toxicology) – Johannes Gutenberg University of Mainz, Germany

Cumulative Thesis: Consequences of DNA damage for gene transcription: direct effects of modified nucleobases and the role of base excision repair

1999

Ph.D. (Biology/Oncology) – R.E.Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, Kyiv, Ukraine


1995

Diploma and state examination (Biology/Immunology) – National Taras Shevchenko University of Kyiv, Ukraine (honours)



RESEARCH TOPICS and EXPERTISE

  • Genotoxicity of drugs and chemicals
  • DNA repair and DNA damage response
  • Human DNA Repair diseases
  • Interactions between DNA damage and transcription
  • Epigenetic regulation and dynamics of epigenetic marks
  • Molecular and biochemical pharmacology of DNA topoisomerases

POSITIONS HELD


2016–present

Heisenberg Fellow of the DFG, Group Leader “Responses to DNA Damage” at the Institute of Toxicology, University Medical Center Mainz

2013–present

Lecturer (Privatdozent) at the Faculty of Chemistry, Pharmacy and Geological Sciences, Johannes Gutenberg University of Mainz

2005–2016

Research Scientist at the Institute of Pharmacy and Biochemistry, Johannes Gutenberg University of Mainz, Germany (Pharmacology and Toxicology, with Prof. Bernd Epe)

2000–2005

Research Fellow at the Department of Biochemistry “G. Moruzzi”, University of Bologna, Italy (Biochemical Pharmacology, with Prof. Giovanni Capranico)

1999–2000

Junior Research Associate at the R.E.Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, Kyiv, Ukraine (Tumour Cell Biology, with Prof. Petro Pogrebnoy)



UNIVERSITY TEACHING

presentPharmacology and Toxicology of Xenobiotics, Graduate Programme in Pharmacy, University of Mainz, Germany (seminars, since 2011)

formerGeneral Biology for Pharmacists (Part “Genetics”), Graduate Programme in Pharmacy, University of Mainz, Germany (lectures, 2011–2014)

Demonstration course “Genotoxicity and Mutagenesis”, Graduate Programme in Pharmacy, University of Mainz, Germany (seminars and laboratory course, 2007–2012)

Functional Protein Interactions in the Nucleus, Graduate Programme in Biotechnology, University of Bologna, Italy (seminars and laboratory course, 2005)


SELECTED AWARDS AND MERITS

  • Heisenberg Fellowship of the German Research Foundation (2016)
  • Sanofi-Aventis Prize of the German Society of Toxicology for the best short talk at the 51st Annual DGPT Meeting (2010)
  • European Environmental Mutagen Society Young Scientist (YSTA) Award (2009)
  • Marie-Curie Research Training Fellowship (2005–2007)
  • Pezcoller Foundation/AACR Scholar-in-Training Award (2003)
  • IARC/WHO Postdoctoral Research Fellowship (2000)
  • Individual postgraduate student award #PSU084050 of the Open Society Institute (U.S.A.) and the Government of Ukraine (1998)
  • Mykhailo Hrushevsky Honorary Scholarship (1994)

LECTURING OUTSIDE THE ACADEMIA


Invited lecturer at the yearly advanced course “Molecular and Cellular Toxicology” of the German Society of Pharmacology and Toxicology (DGPT)


SCIENTIFIC MENTORING

  • 11 diploma/master theses students 
  • 5 Ph.D. students (3 completed with “magna cum laude”, 2 in progress)

OTHER ADVISORY APPOINTMENTS


  • Member of five Thesis Advisory Committees of the International PhD Programme (IPP) coordinated by the Institute of Molecular Biology (IMB, Mainz) (since 2015)
  • Member of the IPP candidate evaluation panels at the IMB, Mainz (since 2015)
  • Tutor of the International Summer School coordinated by the IMB, Mainz (2016)

MEMBERSHIP IN SCIENTIFIC SOCIETIES


Full member
  • German DNA Repair Society (since 2008)
  • German Society of Toxicology (since 2009)
Associate member
  • American Association for Cancer Research (since 2003)

SCIENTIFIC REVIEWING


Journals
  • Journal of Cell Science
  • Mutation Research
  • Chemical Research in Toxicology
  • Free Radical Biology and Medicine
  • Scientific Reports
  • Cancer Letters
  • Gene
  • Genes
  • Chemical Science
  • International Journal of Molecular Sciences
  • Photochemical and Photobiological Sciences
Funding Agencies
  • Wellcome Trust
  • Netherlands Organisation for Scientific Research (NWO)
  • The National Science Centre / Narodowe Centrum Nauki (Poland)


Publications (PubMed)

Current Third-Party Funding (German Research Foundation)

Researcher Profile (ResearcherID)

Researcher Profile (ORCID)

lab
Andriy Khobta (CV)
Team
Former Members / Alumni

research
Research Profile and Directions
Current Funding

publications

positions

pages

partners

links






Last modified 9 November, 2017 



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