DES S-box: | S1 | S2 | S3 | S4 | S5 | S6 | S7 | S8 |
linear potential: | 81/256 | 1/4 | 1/4 | 1/4 | 25/64 | 49/256 | 81/256 | 1/4 |
differential potential: | 1/4 | 1/4 | 1/4 | 1/4 | 1/4 | 1/4 | 1/4 | 1/4 |
It was known since a long time—but if not we would see it now: The designers of DES knew about differential cryptanalysis, as is evident from the uniformly low differential potential. The somewhat chaotic linear potential suggests the they didn't yet know about linear cryptanalysis.
In particular the »bad« value 25/64 = 100/256 for S5 reveals a remarkable weakness.