Dr Giovanni Settanni
Theoretical and computational biophysics
Since the discovery of the
one-to-one correspondence between protein sequences and
their unique three dimensional structure many aspects of
the folding process of proteins have been elucidated,
although a non-anecdotal and synthetic view of the problem
is still elusive. Theoretical and computational approaches
have helped to explain the basic physical principles
underlying a folding system and some important features of
the free energy landscape of proteins. With the steady
increase in available computer power, computational
methods are an increasingly important tool for studying
the folding, dynamics and interactions of biological
molecules. Here, we apply these methods to study several
interesting biological system and develop novel analysis
instruments able to synthesize the results of our
simulations in a productive way.